Unfortunately for many people the answer is – VERY.
When I asked this question recently, RB kindly replied to me and I have to say that I recognise much of what he says:
“Akathisia, depersonalisation and derealisation are 3 of its [Seroxat] most insidious side effects.
Akathisia is an extreme inner restlessness, a nervous system in total overdrive, depersonalisation is when the drug creates a state of being equivalent to an annihilation of the personality, so severe in fact that the sufferer will do things not just out of character but also without conscience or reason and combine these with derealisation (Seroxat inducing a trance-like effect) where the user loses all sense of reality.
Combine all 3 with an already emotionally fragile individual and you have a chemically induced timebomb. The Seroxat murders and seroxat suicides have all been attributed to these horrible side effects”.
From my experience, I have to say that looking back on my time taking Seroxat, I can recognise the depersonalisation and derealisation all too well. But they don’t suddenly start once you take the drug – they are truely “insidious”- they creep up slowly on you after a number of years and you simply become a different person.
Akathisia (an extreme inner restlessness) was one of the things I suffered from during withdrawal. It manifests itself physically as well – you simply cannot sit or lie still for any length of time – you just can’t ‘settle’.