Seroxat increases suicidal thinking – it’s official – but what about addiction and withdrawal?

Seroxat increases suicidal thoughts – it’s official, or at least it will be official
from October this year. But only if you’re 25 years old or younger…

… if you’re older, even by a month or just a day, then you’re safe – so they
tell us and GlaxoSmithKline always tells us the truth, don’t you agree?

But no mention of withdrawal or addiction.

WARNINGS of the dangers of suicidal thoughts and behaviour are to be
included in the packages of anti-depressants in the UK. Warnings will be
carried in the patient information leaflet in the packets from October this

The direction was issued yesterday (Tuesday) by the Government’s
Medicines and Healthcare Products Regulatory Agency. (MHRA)

A notice has been sent to drug manufacturers. It mentions a review by
the Food and Drugs Agency in America, which looked at bupropion,
citalopram, duloxetine, escitalopram, fluoxetine, fluvoxamine,
mirtazapine, nefazodone, paroxetine, sertraline and venlaxfaxine.

The review found no risk of higher sucidality in the general
population but said younger people were at higher risk and that there
were no differences in the risk between antidepressant classes.

A statement released by the MHRA says that the wording of warnings has
been agreed by the EU as has the time table for implementation.

The agreed wording reads:

“Thoughts of suicide and worsening of your depression or anxiety
disorder. If you are depressed and/or have anxiety disorders, you can
sometimes have thoughts of harming or killing yourself. These may be
increased when first starting antidepressants, since these medicines
all take time to work, usually about two weeks but sometimes longer.

You may be more likely to think like this:

If you have previously had thoughts about killing or harming yourself.

If you are a young adult.

Information from clinical trials has shown an increased risk of
suicidal behaviour in young adults aged less than 25 years with
psychiatric conditions who were treated with an antidepressant.

If you have thoughts of harming or killing yourself at any time,
contact your doctor or go to a hospital straight away.

You may find it helpful to tell a relative or close friend that you
are depressed or have an anxiety disorder and ask them to read this
leaflet. You might ask them to tell you if they think your depression
or anxiety is getting worse or if they are worried about changes in
your behaviour.”

The news was greeted as a victory by anti-drugs campaigner, Janice
Simmons, a grandmother from Great Stukeley in Huntingdon.

Mrs Simmons told The Hunts Post on Tuesday: “I’ve won. This is the
result of eight years’ work. Warnings of suicidal thoughts and
behaviour will now be carried on all anti-depressants.”

Mrs Simmons, 57, began her campaign after she discovered that her
second husband, John had been prescribed Seroxat years before she met
him and since become addicted to anti-depressants. Her help-group –
the Seroxat User Group – has had tens of thousands of hits on its
website. Mrs Simmons has gathered information from across the world.
She has begun a dossier of case histories of tragic effects on people
who have been prescribed anti-depressants.

This year she had a meeting with the Prime Minister, Gordon Brown to
discuss the problem. However, she has always conceded that the drugs
can help some people.

One of the issues Mrs Simmons discussed with Gordon Brown was the
length of time (four years) that the MHRA has taken to investigate
allegations against the manufacturer of Seroxat, GlaxoSmithKline

It is alleged that the drugs giant withheld information that Seroxat
could cause suicide in under 18s. The allegations have always been
denied and GSK has said that Seroxat was never licensed for children.

Too little too late is what I say


4 Responses to “Seroxat increases suicidal thinking – it’s official – but what about addiction and withdrawal?”


    It reminds me of a classic Springsteen line ‘One Step Forward, Two Steps Back’

    Not content with allowing children to suffer since the launch of Seroxat, the MHRA are now going to sit back and watch anyone over the age of 25 suffer!

    It’s a step in the right direction for sure… but two steps back in the wrong direction.


  2. Truthman Says:

    This is a small victory for mental health advocates, and SSRI survivors ..

    But there is a long way to go…

  3. pythia Says:

    So what will the next step be? Another ten years and then perhaps a warning about suicidal thoughts in people under the age of forty? The another ten to get a warning about homicidal thoughts in the under eighteeens etc, etc. Great, eh? How long before they warn about years of withdrawal invented in hell? With a bit of luck, more efficient government agencies, a life after this one and eye sight good enough we may be able to read the whole truth from heaven – if there is such a place – some 50 years or so after we have died of natural causes or killed ourselves to escape withdrawal misery.

  4. Rachel tracey Says:

    My husband killed himself shortly after being put on seroxat , I have always known that this dangerous drug was to blame , he had not had thoughts of killing himself in years , his personally changed over a very short time , and I could not read his mood the same as I had been able too, he had be ill for 7 years and over this time we had learned coping mechanisms , but after he was put on seroxat he was a different person , at 6 months pregnant , I went to an anti-natal class , when I returned home he had hung himself, if I had been stronger at this time I would have taken this company on , but I was not , we were never told the risks , thus drug killed my husband and robbed my daughter of her dad , I never got in another relationship , so it robbed me of any future children that I was going to have , this drug should be banned , it is very , very dangerous, and if the makers don’t like what I have just said , they can contact me at,, I’m much stronger now .Rachel Tracey widow of Lionel Gordon Tracey

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